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High Containment Compression of Potent Tablets

12th Dec 2010

Manufacturing highly potent tablets has challenges at every stage of tablet manufacture, but probably the most challenging stage is the tablet compression stage itself.

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 The main challenges include:

  • The complex mechanical design and constuction of the tablet press internal areas.
  • The continuous flor of materials into and out of the tablet press.
  • Cleaning of the tablet press.
  • The multiple interfaces between the tablet press and its enviroment (air inlet, tablet outlet, powder inlet, dust extraction), all of which require a contained interconnection. 
  • Frequent tablet sampling for IPC - either manually or automatically.

Read technical paper:  GEA Courtoy's High Containment in Tablet Compression